SanBio Stroke Study
A Study of Modified Stem Cells (SB623) in Stable Ischemic Stroke
This study is taking place at Stanford University School of Medicine and University of Pittsburgh Medical Center. Santa Clara Valley Medical Center Rehabilitation Research Center is involved in patient recruitment and preliminary screening. This study is funded by SanBio, Inc. and the details can be found on the ClinicalTrials.gov website with the Identifier NCT01287936.
Principal Investigators: Gary K Steinberg, M.D., Ph.D., Neil E Schwartz, M.D., Stanford University School of Medicine. Douglas Kondziolka, MD, FRCSC, Lawrence R. Wechsler, M.D., University of Pittsburgh Medical Center.
Purpose: The primary purpose of the clinical study is to determine the safety of a modified stem cell SB623 when administered to chronic, stable ischemic stroke patients. A second purpose is to determine whether SB623 might improve stroke symptoms. Chronic, stable ischemic stroke patients must be between 6 and 36 months after their stroke, and with only this one prior stroke, and with no further significant improvement from physical therapy.
Participation: Individuals must have suffered a stroke within 36 months, must be 18-75 years old, must have arm or leg weakness, must not have more than one stroke, must have suffered an ischemic stroke and must not have a history of seizures. Potential participants will go through a phone screening, onsite screening, receive modified stem cells treatment and will take part in a two-year follow up.
To date, the first 6 patients, of a total of 18, have been successfully administered SB623. For details, please refer to http://www.san-bio.com/news/documents/SanBio_First_Cohort_2012.03.20.pdf.
In the Silicon Valley/San Jose Area, the company developing the product used in the study was awarded “Idea & Innovation Award 2012” by Silicon Valley/San Jose Business Journal in February 2012. AWARD - Bioscience: SanBio creates better odds for stroke recovery. For details, please refer to http://www.bizjournals.com/sanjose/print-edition/2012/02/17/better-odds-for-stroke-recovery.html.